A Discussion Between Dr. Brian Hooker and Dr. Ryan Cole Exposes a Catastrophic Oversight in COVID-19 mRNA Vaccine Science
Two respected voices—Dr. Brian Hooker and Dr. Ryan Cole—are warning that what was once dismissed as “impossible” is now showing up in the data. Their discussion raises an alarming question: have we crossed a line from temporary medical intervention into permanent, unpredictable genetic alteration?
mRNA Integration Into the Human Genome: No Longer Theoretical
A critical study on a human liver cell line has revealed that portions of COVID-19 vaccine mRNA can reverse-transcribe and integrate into DNA. This upends one of the central assurances given to the public: that mRNA vaccines do not interact with or change our genetic material.
If this finding holds across other tissues, the implications for human health could be profound.
Why This Could Be a Game-Changer
- Mutagenesis & Cancer
DNA is the “source code” of life. Random insertions—like typos—can scramble its instructions, leading to malformed proteins. When such disruptions occur near tumor-suppressor genes (like p53) or oncogenes, they open a direct path toward mutagenesis and cancer development. - Germline Mutation Threat
The lipid nanoparticle (LNP) delivery system used for mRNA vaccines does not remain at the injection site. Biodistribution studies show it travels to the liver, spleen, bone marrow, brain, and—most critically—the ovaries and testes. That means potential genetic damage isn’t limited to one person. It raises the unsettling prospect of heritable germline mutations passed to future generations. - Disarming Our Defenses
Dr. Cole also highlights peer-reviewed evidence that the spike protein itself binds to and disrupts p53, the “guardian of the genome,” and BRCA genes, which are crucial for suppressing breast and ovarian cancers. In other words, we may be injecting a substance that actively undermines our cells’ most critical defense systems.
The Deafening Silence of the Scientific Establishment
According to Dr. Cole, the NIH should be urgently funding studies to answer essential questions:
Is this material integrating into neural tissue?
Is it causing germline mutations?
Yet, despite mounting signals, large-scale, independent safety studies remain unfunded and largely absent. The public has been told “it stays in the arm” and “it doesn’t affect DNA,” but those claims no longer stand unchallenged.
A Crossroads for Public Health
If Hooker and Cole’s warnings are validated, the era of assuming that mRNA vaccines are inherently non-genotoxic is over. The stakes are generational: not just individual health, but potentially permanent changes to human genetics. At minimum, the findings demand urgent, transparent research—not silence.


