Australian Childhood & Adolescent Vaccination Schedule – Full Antigen Count
Before diving into the numbers, a few key points:
- Antigen definition: An antigen is any substance from a virus or bacterium that your immune system recognizes as “foreign” and responds to. Vaccines use antigens to train the immune system to recognize and fight specific diseases.
- Why ~85 antigens but only ~14–16 diseases?
- Boosters: Many vaccines require multiple doses over time to maintain immunity. Each repeated dose counts as another antigen exposure.
- Multiple strains: Some diseases have different strains (e.g., pneumococcal disease), and vaccines include antigens for each strain.
- Combination vaccines: Many injections contain multiple antigens in a single shot, but each antigen is disease-specific.
For context, 50 years ago, Australian children received far fewer antigens — roughly 10–15 antigens by the same age — because there were fewer vaccines, fewer combination shots, and fewer booster doses.
0–4 Years: Childhood Vaccines
| Age | Vaccine(s) | Shots | Antigens per shot | Total antigens | Notes |
|---|---|---|---|---|---|
| Birth | Hepatitis B | 1 | 1 | 1 | Single antigen |
| 2 months | DTPa (Diphtheria, Tetanus, Pertussis), IPV (Polio), Hib, Hep B, PCV13 (Pneumococcal) | 2 | Shot 1: DTPa/Hep B/Hib = 5, Shot 2: PCV13 = 13 | 18 | First doses |
| 4 months | Same as 2 months | 2 | 5 + 13 | 18 | Second doses / boosters |
| 6 months | Same as 2 months | 2 | 5 + 13 | 18 | Third doses / boosters |
| 12 months | MMR (Measles, Mumps, Rubella), Varicella, Hib booster, PCV booster | 2 | Shot 1: MMR = 3, Shot 2: Varicella + Hib + PCV = 1 + 1 + 13 = 15 | 18 | First major boosters |
| 18 months | DTPa booster | 1 | 3 (D, T, P) | 3 | Booster |
| 4 years | DTPa booster, IPV | 2 | DTPa = 3, IPV = 1 | 4 | Pre-school boosters |
Subtotal by age 4: – Total shots: 12 – Total antigens received: 80
12–13 Years: Adolescent Vaccines
| Age | Vaccine(s) | Shots | Antigens per shot | Total antigens | Notes |
|---|---|---|---|---|---|
| 12–13 years | HPV 2 doses, Boostrix (Tdap) | 3 | HPV: 1 each dose = 2, Boostrix (Tdap) = 3 | 5 | Booster + protection against new disease (HPV) |
Subtotal by age 12–13: – Additional shots: 3 – Additional antigens: 5
Grand Total by Adulthood
- Total shots (birth to adolescent vaccines): 15
- Total antigens (counting all boosters and combination components): 85
- Total diseases covered: ~14–16 (some antigens cover multiple strains, e.g., PCV13 counts as 13 antigens for different pneumococcal strains)
- Boosters included: All repeated antigens are counted individually
Summary Statement
By the time an Australian reaches adolescence:
- They have received ~15 injections containing ~85 individual antigens, including all boosters.
- These antigens protect against ~14–16 diseases.
- The high antigen count relative to the number of diseases is due to boosters, multiple strains of the same disease, and combination vaccines.
- In comparison, 50 years ago, children received far fewer antigens — roughly 10–15 — because fewer vaccines and boosters existed.
Excerpt Summary
Australian children receive vaccines containing multiple antigens to protect against specific diseases. An antigen is a substance from a virus or bacterium that triggers the immune system to recognize and fight the disease. By age 4, children typically receive ~12 injections containing ~80 antigens, covering ~14–16 diseases. Boosters and vaccines covering multiple strains increase the total antigen count. By adolescence (12–13 years), additional vaccines like HPV and Tdap add ~3 more shots and ~5 more antigens, bringing the total to ~15 injections and ~85 antigens. Compared to 50 years ago, children received far fewer antigens (~10–15) due to fewer vaccines and boosters.
Print PDF
Australian-Vaccine-Antigen-Count


