In this important discussion, I sit down with Geert Vanden Bossche to explore his latest thinking on the current trajectory of SARS-CoV-2 and why he believes the pandemic has still not transitioned into a true endemic phase. We look at his recent statements from Voice for Science and Solidarity and his Substack, including the idea that the apparent calm may be misleading, and that the virus-host relationship remains unstable rather than settled.
We also discuss what this could mean clinically and immunologically, including immune escape, persistent infection, chronic immune dysfunction, and whether medicine may be looking for the wrong signals. Whether you agree fully with Geert or not, this conversation is designed to examine his arguments carefully, test the logic behind them, and ask what clinicians and the wider public should be paying attention to next.
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